Alexandra Bouvier is born in Paris in 1900, at the dawn of a new century. From an early age, she is encouraged to think for herself by her enlightened family: her father, a French doctor; her mother, an American nurse; and her maternal grandfather, a highly regarded newspaperman back in the Midwest. At age 14, Alex's comfortable life is upended as war erupts across Europe. Her parents follow their sense of duty to the front, performing triage at a field hospital and confronting the horrors of poison gas and trench warfare. The merciless fighting, coupled with the fast-spreading Spanish flu, wreaks havoc on the continent, as well as on Alex's loved ones. By the time she is 18, she has suffered unimaginable losses. With her grandfather's support, she attends the University of Chicago and decides to follow his footsteps into journalism. As a newspaper intern, she meets reporter Oliver Foster, who is covering the gang wars sparked by Prohibition. He too has known devastating loss, and the two are drawn to each other, though both fear any attachment. As it turns out, Alex has good reason to be cautious.